The most effective natural Memory treatment
Click on a box to see what we consider
the most effective natural Memory treatment for you

WOMEN 39
AND UNDER
 MEN 39
AND UNDER
 WOMEN 40
AND UP
 MEN 40
AND UP
click here...click here...click here...click here...

Your memory is not what it used to be

There are many causes of reduced short- or long-term memory including stress, pollution, and reduced cerebral blood flow due to atherosclerosis or triggered by blood vessel contraction, and neurodegenerative illnesses such as Parkinson’s and Alzheimer’s. Treatment should be aimed at enhancing cerebral blood flow and treating the triggering causes such as stress (oxidative stress) and/or neurodegenerative diseases.

Which natural ingredients can have an effect on memory?

The recommendations listed below are based on more than 4,383 scientific studies. The ability of ginkgo biloba to significantly improve cerebral blood flow and cognitive capacity is extremely well documented in more than 108 double-blind scientific studies.

The combination of ginkgo biloba and Siberian ginseng has been proven to lower heightened plasma cortisol and adrenaline significantly, thereby enhancing the individual's stress-tolerance. Oxidative stress is counteracted by supplementation with alpha-lipoic acid, N-acetylcysteine, tocotrienols, coenzyme Q10, green tea extract, certain vitamins and minerals and many more natural substances.

What effects do these ingredients have?

  • Improve memory – both short- and long-term memory.
  • Improve cognitive functions – such as reaction time and other important cognitive brain functions.
  • Improve stress tolerance enabling the individual to tolerate more stress before she/he reacts to it.
  • Improve overall well-being.
  • Improve mental alertness and the ability to concentrate.
  • Promote better mood.
  • Improve energy levels.
  • May prevent and even delay the progression of existing Alzheimer’s disease.
  • Reduce oxidative stress.

For the reader with a deeper interest:

How do these ingredients work?

  • Treat and prevent vitamin and mineral deficiencies.
  • Improve blood flow to the brain and other important organs.
  • Have significant vasodilating effect.
  • Function as potent antioxidants.
  • Lower high cortisone and adrenaline levels.
  • Chelate and neutralize toxic substances such as mercury, arsenic, chromium, cadmium, lead and other toxins.
  • Support the body’s excretion of anesthesia, painkillers and many other medications.
  • Protect mitochondria against deformation during ischemic attack.
  • Stimulate mitochondria to produce more ATP (energy) in the cells.
  • Impede the depletion of metabolites necessary for ATP synthesis.

The information above is based on more than 8,000 articles published in scientific journals and which are available at MEDLINE. Below you will find a few of them listed:

References

  1. Amenta F, Parnetti L, et al. Treatment of cognitive dysfunction associated with Alzheimer’s disease with cholinergic precursors: Ineffective treatments or inappropriate approaches? Mech Ageing Dev. 2001 Nov;122(16):2025–40.
  2. Arrigo A, Casale R, Buonocore M, Ciano C. Effects of acetyl-L-carnitine on reaction times in patients with cerebrovascular insufficiency. Int J Clin Pharmacol Res. 1990;10:133-137.[Medline]
  3. Barak Y, Levine J, Glasman A, Elizur A, Belmaker RH. Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trial. Prog Neuropsychopharmacol Biol Psychiatry. 1996;20:729-735.[Medline]
  4. Benton D, Fordy J, et al. The impact of long-term vitamin supplementation on cognitive functioning. Psychopharmacol.1995:117;298–305.
  5. Bonavita E. Study of the efficacy and tolerability of L-acetylcarnitine therapy in the senile brain. Int J Clin Pharmacol Ther Toxicol. 1986;24:511-516.[Medline]
  6. Brooks JO, Yesavage JA, Carta A, Bravi D. Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach. Int Psychogeriatr. 1998;10:193-203.[Medline]
  7. Bryan J, Calvaresi E, Hughes D. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. J Nutr. 2002;132:1345-1356.[Abstract/Free Full Text]
  8. Calvaresi E, Bryan J. B vitamins, cognition, and aging: a review. J Gerontol B Psychol Sci Soc Sci. 2001;56:327-339.
  9. Chandra RK. Effect of vitamin and trace-element supplementation on cognitive function in elderly subjects. Nutrition. 2001;17:709-712.[Medline]
  10. Crook TH, Tinklenberg J, et al. Effects of phosphatidylserine in age-associated memory impairment. Neurology. 1991 May;41(5):644–9.
  11. De Hoz L, Martin SJ, et al. Neural basis of memory loss. Plos Biol. 2004;2(8):e225.
  12. de Jong N, Chin A Paw MJ, de Groot LC, et al. Nutrient-dense foods and exercise in frail elderly: effects on B vitamins, homocysteine, methylmalonic acid, and neuropsychological functioning. Am J Clin Nutr. 2001;73:338-346.[Abstract/Free Full Text]
  13. Deijen JB, van der Beek EJ, Orlebeke JF, van den Berg H. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort. Psychopharmacology (Berlin). 1992;109:489-496.[Medline]
  14. Delwaide PJ, Gyselynck-Mambourg AM, et al. Double-blind randomized controlled study of phosphatidylserine in senile demented patients. Acta Neurol Scand. 1986 Feb;73(2):136–40.
  15. Funfgeld EW, Baggen M, et al. Double-blind study with phosphatidylserine (PS) in parkinsonian patients with senile dementia of Alzheimer’s type (SDAT). Prog Clin Biol Res. 1989;317:1235–46.
  16. Galduroz JC, Carlini EA. The effects of long-term administration of guarana on the cognition of normal, elderly volunteers. Rev Paul Med. 1996;114:1073-1078.
  17. Goncharova ND, Lapin BA. Effects of aging on hypothalamic-pituitary-adrenal system function in non-human primates. Mech Ageing Dev. 2002 Apr 30;123(8):1191–201.
  18. Gonzalez-Gross M, Marcos A, Pietrzik K. Nutrition and cognitive impairment in the elderly. Br J Nutr. 2001;86:313-321.[Medline]
  19. Goodwin JS, Goodwin JM, Garry PJ. Association between nutritional status and cognitive functioning in a healthy elderly population. JAMA. 1983;249:2917-2921.[Abstract]
  20. Grodstein F, Chen J, et al. High-dose antioxidant supplements and cognitive function in community-dwelling elderly women. Am J Clin Nutr. 2003 Apr;77:975–84.
  21. Halliwell B, Gutteridge JMC. Oxygen radicals in the nervous system. Trends Neurosci. 1985;8:22–6.
  22. Hara H, Kato H, et al. Protective effect of alpha-tocopherol on ischemic neuronal damage in the gerbil hippocampus. Brain Res.1990;510:335–8.
  23. Herrmann WM, Dietrich B, Hiersemenzel R. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance—acetyl-L-carnitine—in patients with organic brain syndrome. Int J Clin Pharmacol Res. 1990;10:81-84.[Medline]
  24. Hogarth MB, Marshall P, Lovat LB, et al. Nutritional supplementation in elderly medical in-patients: a double-blind placebo-controlled trial. Age Ageing. 1996;25:453-457.[Abstract/Free Full Text]
  25. Huijbregts PP, Feskens EJ, Rasanen L, et al. Dietary patterns and cognitive function in elderly men in Finland, Italy and The Netherlands. Eur J Clin Nutr. 1998;52:826-831.[Medline]
  26. Jorissen BL, Riedel WJ. Nutrients, age and cognition. Clin Nutr. 2002;21:89-95.[Medline]
  27. Kalmijn S, Feskens EJ, Launer LJ, Kromhout D. Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men. Am J Epidemiol. 1997;145:33-41.[Abstract/Free Full Text]
  28. Karishma KK, Herbert J. Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone-induced suppression. Eur J Neurosci. 2002 Aug;16(3):445–53.
  29. Kasper DL, Braunwald DE, et al. Harrison's Principles of Internal Medicine. 16th ed. New York: McGraw-Hill Professional; 2005.
  30. Kleijnen J, Knipschild P. Gingko biloba for cerebral insufficiency. Br J Clin Pharmacol. 1992 Oct 16;14(5):316–20.
  31. Koistinaho M, Koistinaho J. Interactions between Alzheimer’s disease and cerebral ischemia: Focus on inflammation. Brain Res Brain Res Rev. 2005 Apr;48(2):240–50.
  32. Kuboyama T, Tohda C, et al. Neuritic regeneration and synaptic reconstruction induced by withanolide A. Br J Pharmacol. 2005 Apr;144(7):961–71.
  33. La Rue A, Koehler KM, Wayne SJ, Chiulli SJ, Haaland KY, Garry PJ. Nutritional status and cognitive functioning in a normally aging sample: a 6-y reassessment. Am J Clin Nutr. 1997;65:20-29.[Abstract/Free Full Text]
  34. Li MH, Jang JH, et al. Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death. Ann NY Acad Sci. 2004 Dec;1030:317–29.
  35. Martin A, Youdim K, Szprengiel A, Shukitt-Hale B, Joseph J. Roles of vitamins E and C on neurodegenerative diseases and cognitive performance. Nutr Rev. 2002;60:308-326.[Medline]
  36. Martin DC, Francis J, Protetch J, Huff FJ. Time dependency of cognitive recovery with cobalamin replacement: report of a pilot study. J Am Geriatr Soc. 1992;40:168-172.[Medline]
  37. Masaki KH, Losonczy KG, Izmirlian G, et al. Association of vitamin E and C supplement use with cognitive function and dementia in elderly men. Neurology. 2000;54:1265-1272.[Abstract/Free Full Text]
  38. Mathis C, Meziane H, et al. Models for the study of memory and neurosteroids. J Soc Biol. 1999;193(3):299–306.
  39. Meador K, Loring D, et al. Preliminary findings of high dose thiamine in dementia of Alzheimer’s type. J Geriatr Psychiatry Neurol.1993a;6:222–9.
  40. Meador K, Loring D, Nichols M, et al. Preliminary findings of high-dose thiamine in dementia of Alzheimer's type. J Geriatr Psychiatry Neurol. 1993;6:222-229.
  41. Meador K, Nichols ME, et al. Evidence for a central cholingeric effect of high dose thiamine. Ann Neurol.1993b;34:724–6.
  42. Miyamoto M, Murphy TH, et al. Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line. J Pharmacol Exp Ther. 1989 Sep;250(3):1132–40.
  43. Nolan KA, Black RS, Sheu KF, Langberg J, Blass JP. A trial of thiamine in Alzheimer's disease. Arch Neurol. 1991;48:81-83.[Abstract/Free Full Text]
  44. Passeri M, Cucinotta D, Bonati PA, Iannuccelli M, Parnetti L, Senin U. Acetyl-L-carnitine in the treatment of mildly demented elderly patients. Int J Clin Pharmacol Res. 1990;10:75-79.[Medline]
  45. Racchi M, Govoni S, et al. DHEA and the relationship with aging and memory: A possible link with protein kinase C functional machinery. Brain Res Brain Res Rev. 2001 Nov;37(1–3):287–93.
  46. Rai G, Wright G, Scott L, Beston B, Rest J, Exton-Smith AN. Double-blind, placebo controlled study of acetyl-l-carnitine in patients with Alzheimer's dementia. Curr Med Res Opin. 1990;11:638-647.[Medline]
  47. Riggs KM, Spiro A, Tucker K, Rush D. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. Am J Clin Nutr. 1996;63:306-314.[Abstract/Free Full Text]
  48. Sano M, Bell K, Cote L, et al. Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's disease. Arch Neurol. 1992;49:1137-1141.[Abstract/Free Full Text]
  49. Sano M, Ernesto C, Thomas RG, et al. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. N Engl J Med. 1997;336:1216-1222.[Abstract/Free Full Text]
  50. Schreiber S, Kampf-Sherf O, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci. 2000;37(4):302–7.
  51. Seal EC, Metz J, Flicker L, Melny J. A randomized, double-blind, placebo-controlled study of oral vitamin B12 supplementation in older patients with subnormal or borderline serum vitamin B12 concentrations. J Am Geriatr Soc. 2002;50:146-151.[Medline]
  52. Selhub J, Bagley LC, Miller J, Rosenberg IH. B vitamins, homocysteine, and neurocognitive function in the elderly. Am J Clin Nutr. 2000;71:614S-620S.
  53. Smidt LJ, Cremin FM, et al. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency. J Gerontol.1991;46(1):M16–M22.
  54. Snowdon DA, Tully CL, Smith CD, Riley KP, Markesbery WR. Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun study. Am J Clin Nutr. 2000;71:993-998.[Abstract/Free Full Text]
  55. Solfrizzi V, Panza F, Torres F, et al. High monounsaturated fatty acids intake protects against age-related cognitive decline. Neurology. 1999;52:1563-1569.[Abstract/Free Full Text]
  56. Spagnoli A, Lucca U, Menasce G, et al. Long-term acetyl-L-carnitine treatment in Alzheimer's disease. Neurology. 1991;41:1726-1732.[Abstract/Free Full Text]
  57. Tan RS, Pu SJ. The andropause and memory loss: Is there a link between androgen decline and dementia in the aging male? Asian J Androl. 2001;3(3):169–74.
  58. Thal LJ, Calvani M, Amato A, Carta A. A 1-year controlled trial of acetyl-l-carnitine in early-onset AD. Neurology. 2000;55:805-810.[Abstract/Free Full Text]
  59. Thal LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology. 1996;47:705-711.[Abstract/Free Full Text]
  60. Verhagen AP, de Vet HC, de Bie RA, et al. The Delphi list: a criteria list for quality assessment of randomized clinical trials for conducting systematic reviews developed by Delphi consensus. J Clin Epidemiol. 1998;51:1235-1241.[Medline]